Depression with delusions or voices requires rapid specialist help. Read what this means, what treatment is possible and what loved ones can do.
Psychotic experiences can feel very convincing and affect safety or self-care. This page provides explanations for patients and relatives; do not wait for self-help in case of new or increasing symptoms.
Zorgfuik provides general information and does not make a diagnosis. Discuss personal symptoms, treatment and medication with a qualified healthcare provider.
Sources checked for . Information for adults and relatives; new psychotic symptoms require professional assessment.
What are psychotic features of depression?
In severe depression, contact with reality can be disrupted. For example, someone may have delusions or hallucinations. The belief that something terrible is happening can feel completely real to that person, even if others don't recognise it.
Delusions
A strong belief that does not match reality and is difficult to correct. For example, that you have caused a disaster, that your family has been ruined through your fault or that a body part no longer exists. The content alone does not provide a diagnosis.
Hallucinations
Perceptions that others do not share, such as hearing voices without anyone speaking. Voices can be accusatory or threatening. Also tell a care provider if voices give orders.
Psychotic experiences do not automatically mean schizophrenia. They can occur with various conditions and conditions. In psychotic depression, the psychiatrist assesses how the experiences are related to the depressive episode.
Severe guilt or worry is not automatically a delusion. The healthcare professional examines, among other things, persuasion, sense of reality, mood, behaviour and progress. An online test or discussion with a loved one cannot replace that research.
The assessment also covers food, drink, sleep, medication, alcohol or other drugs, and physical health. For example, sudden confusion may have a physical cause. Previous manic episodes or a recent birth also change the decision.
Report immediately if someone no longer moves or speaks, no longer drinks, seriously neglects themselves or wants to harm themselves. Such signals may require intensive medical and psychiatric care.
Treatment takes place in specialist mental health care. The team assesses whether intensive care at home can be done safely or whether admission is necessary. The choice depends on physical condition, risks, support and preferences. Not everyone with psychotic symptoms is automatically admitted.
Antidepressant and antipsychotic
The Dutch guideline usually recommends a combination. The antidepressant targets the depression; the antipsychotic targets psychotic symptoms. Using only one of these is not the recommended standard treatment for psychotic depression.
Ask what effect is expected and what monitoring is needed. The medicines and dosages are chosen for the individual; do not combine or stop yourself.
Electroconvulsive therapy (ECT)
ECT can be used early if a quick effect is needed, for example in the event of life-threatening food or fluid refusal or serious suicide risk. So it is not just a final step after years of trying.
An epileptic seizure is induced in a controlled manner under short anesthesia and with a muscle relaxant. This is done in a medical treatment environment, with monitoring and repeated evaluation.
With ECT you discuss, among other things, anesthesia, headache, temporary confusion and memory problems. Memory symptoms can sometimes last longer. Ask how the team follows this and what alternatives are available. Discussions, practical support and recovery care remain important in addition to biological treatment.
Speak calmly and simply. Ask one question at a time. Having many people talking at the same time can be confusing.
Don't turn it into a debate. Don't try to explain away the belief with more and more evidence. Don't confirm the delusion either.
Tell what you see. Note changes in sleep, eating, drinking and behaviour and provide concrete examples to the treatment team.
Organize help. Offer to call or come along together. If it is unsafe, you also call when someone does not see the need.
Protect yourself too. Do not intervene physically if it could become dangerous. Keep your distance and call emergency help in case of immediate danger.
You do not have to make a diagnosis at home or decide on compulsory care. This is a professional assessment with its own conditions. You can provide important information and indicate that you cannot handle the situation safely.
If delusions or voices diminish, the depression may still be present. Restoring concentration, confidence, daily tasks and relationships can take time. Also discuss shame or sadness about what happened during the crisis.
The treatment is not automatically stopped as soon as someone seems calmer. Ask about continuation of medication, side effects, follow-up contacts and the plan for possible reduction. After ECT, follow-up treatment is also necessary to help prevent relapse.
Create an alert plan with your own early signs, contact persons and crisis appointments. Determine who supervises physical recovery and who maintains an overview when multiple professionals are involved.
Which diagnosis fits best, and what other causes have been investigated?
Is staying at home safe, and what support is needed?
Why do we choose this combination or ECT?
What side effects and physical risks are monitored?
Who can be reached outside office hours?
What do we agree about recovery, medication and relapse prevention?
Self-help is not a substitute for treatment in acute psychosis. If you have thoughts of suicide you can also call day and night 0800-0113 or chat via 113 Suicide Prevention; call if there is immediate danger to life 112.
What does depression with psychotic features mean?
That during a depressive episode delusions or hallucinations also occur, such as voices or beliefs that do not match reality. This requires specialist assessment.
Is psychotic depression the same as schizophrenia?
No. Psychosis can occur with various conditions. The course, the relationship with mood and possible other causes are being investigated.
What treatment is usually discussed?
For psychotic depression, a combination of an antidepressant and an antipsychotic is often recommended. ECT may also be considered and sometimes required early for life-threatening severity.
When may ECT be necessary?
For example, in the case of severe or life-threatening symptoms, insufficient food or drink, high suicide risk or insufficient effect of other treatment. The team discusses benefits, risks and alternatives.
Can ECT cause memory problems?
Yes. Temporary confusion and memory symptoms may occur; some memories may remain disturbed for longer. Discuss before and during the treatment how this will be monitored.
How do I respond to a delusion as a loved one?
Acknowledge the fear or tension without confirming the belief as fact. Don't argue fiercely. Seek professional help and ensure your own safety.
When do I call 112?
In case of immediate danger to life. In the event of new psychotic symptoms or a mental health crisis, immediately call your GP, out-of-hours GP service or your own crisis team for assessment.